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OptimizeRx

General
Policy Number: GP-X-103

Last Updated: Sept. 30, 2025

This policy outlines preauthorization procedures for the OptimizeRx Program.

We contract with Prime Therapeutics for review of select medications.

Please submit preauthorization requests directly to GatewayPA.

  • Hours of Operation: 24 hours a day
  • Call toll free: 1-800-424-1709 or fax 1-888-656-6671
  • Website: GatewayPA.com

Prior authorization is not a guarantee of payment. Benefits are based on eligibility at the time of service and are subject to applicable contract terms. 
For more information, please review the Policies and Procedures searchable tool on NebraskaBlue.com/Providers/BCBSNE-Provider-Procedures

Please visit the Blue Cross and Blue Shield of Nebraska Medical Pharmacy Policies page on Gateway to view the complete list of clinical policies specific to Commercial members.